Vash, Livio, and Wormwood, the master and his two disciples meet each other in a deadly face off and they will not all survive.

Train Heartnet faces Creed in a final showdown.

Humanity on a distant, sandy planet is mere days from extinction. And yet there remains a spark of hope. Vash, the Humanoid Typhoon, an unlikely hero with unusual powers, might be the only one to stop his "Brother," Knives, from destroying humanity - though they were both born of human science!

Tim-21, Telsa and Quon finally escape the Machine Moon and head out on a quest to find the ancient robot who may hold the key to the Harvesters. Meanwhile Andy and his rag-tag team close in on Tim, but their fragile alliance is shattered by Driller's revelations.

Train and River put aside their differences as they face off with Shiki, one of the most powerful members of the Apostles of the Stars. Shiki is determined to show that the Tao is the ultimate form of power, and he's going to take down Train, his friends and all of Chronos to prove it!