"Since their mother's death, Carter and Sadie have become near strangers. While Sadie has lived with her grandparents in London, her brother has traveled the world with their father, the brilliant Egyptologist, Dr. Julius Kane. One night, Dr. Kane brings the siblings together for a "research experiment" at the British Museum, where he hopes to set things right for his family. Instead, he unleashes the Egyptian god Set, who banishes him to oblivion...

When Apophis, the chaos snake, threatens to plunge the world into eternal darkness, siblings Carter and Sade Kane plan to use an ancient spell to destroy the snake, but first must rely on the murderous ghost of a powerful magician.

Despite their best efforts, Carter and Sade Kane can't seem to keep Apophis, the chaos snake, down. Their only hope: find an ancient spell that might turn the serpent's own shadow into a weapon.